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A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer
The development and growth of microfluidics has been mainly based on various novel fabrication techniques for downsizing and integration of the micro/nano components. Especially, an effective fabrication technique of three-dimensional structures still continues to be strongly required in order to im...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509039/ https://www.ncbi.nlm.nih.gov/pubmed/28773742 http://dx.doi.org/10.3390/ma9080621 |
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author | Mogi, Katsuo Sakata, Kenshiro Hashimoto, Yuki Yamamoto, Takatoki |
author_facet | Mogi, Katsuo Sakata, Kenshiro Hashimoto, Yuki Yamamoto, Takatoki |
author_sort | Mogi, Katsuo |
collection | PubMed |
description | The development and growth of microfluidics has been mainly based on various novel fabrication techniques for downsizing and integration of the micro/nano components. Especially, an effective fabrication technique of three-dimensional structures still continues to be strongly required in order to improve device performance, functionality, and device packing density because the conventional lamination-based technique for integrating several two-dimensional components is not enough to satisfy the requirement. Although three-dimensional printers have a high potential for becoming an effective tool to fabricate a three-dimensional microstructure, a leak caused by the roughness of a low-precision structure made by a 3D printer is a critical problem when the microfluidic device is composed of several parts. To build a liquid-tight microchannel on such a low-precision structure, we developed a novel assembly technique in which a paraffin polymer was used as a mold for a microchannel of photo-curable silicone elastomer on a rough surface. The shape and roughness of the molded microchannel was in good agreement with the master pattern. Additionally, the seal performance of the microchannel was demonstrated by an experiment of electrophoresis in the microchannel built on a substrate which has a huge roughness and a joint. |
format | Online Article Text |
id | pubmed-5509039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-55090392017-07-28 A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer Mogi, Katsuo Sakata, Kenshiro Hashimoto, Yuki Yamamoto, Takatoki Materials (Basel) Article The development and growth of microfluidics has been mainly based on various novel fabrication techniques for downsizing and integration of the micro/nano components. Especially, an effective fabrication technique of three-dimensional structures still continues to be strongly required in order to improve device performance, functionality, and device packing density because the conventional lamination-based technique for integrating several two-dimensional components is not enough to satisfy the requirement. Although three-dimensional printers have a high potential for becoming an effective tool to fabricate a three-dimensional microstructure, a leak caused by the roughness of a low-precision structure made by a 3D printer is a critical problem when the microfluidic device is composed of several parts. To build a liquid-tight microchannel on such a low-precision structure, we developed a novel assembly technique in which a paraffin polymer was used as a mold for a microchannel of photo-curable silicone elastomer on a rough surface. The shape and roughness of the molded microchannel was in good agreement with the master pattern. Additionally, the seal performance of the microchannel was demonstrated by an experiment of electrophoresis in the microchannel built on a substrate which has a huge roughness and a joint. MDPI 2016-07-27 /pmc/articles/PMC5509039/ /pubmed/28773742 http://dx.doi.org/10.3390/ma9080621 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mogi, Katsuo Sakata, Kenshiro Hashimoto, Yuki Yamamoto, Takatoki A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer |
title | A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer |
title_full | A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer |
title_fullStr | A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer |
title_full_unstemmed | A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer |
title_short | A Novel Fabrication Technique for Liquid-Tight Microchannels by Combination of a Paraffin Polymer and a Photo-Curable Silicone Elastomer |
title_sort | novel fabrication technique for liquid-tight microchannels by combination of a paraffin polymer and a photo-curable silicone elastomer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509039/ https://www.ncbi.nlm.nih.gov/pubmed/28773742 http://dx.doi.org/10.3390/ma9080621 |
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