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Genetic compensation: A phenomenon in search of mechanisms

Several recent studies in a number of model systems including zebrafish, Arabidopsis, and mouse have revealed phenotypic differences between knockouts (i.e., mutants) and knockdowns (e.g., antisense-treated animals). These differences have been attributed to a number of reasons including off-target...

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Detalles Bibliográficos
Autores principales: El-Brolosy, Mohamed A., Stainier, Didier Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509088/
https://www.ncbi.nlm.nih.gov/pubmed/28704371
http://dx.doi.org/10.1371/journal.pgen.1006780

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