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The collαgen III fibril has a “flexi-rod” structure of flexible sequences interspersed with rigid bioactive domains including two with hemostatic roles
Collagen III is critical to the integrity of blood vessels and distensible organs, and in hemostasis. Examination of the human collagen III interactome reveals a nearly identical structural arrangement and charge distribution pattern as for collagen I, with cell interaction domains, fibrillogenesis...
Autores principales: | Parkin, J. Des, San Antonio, James D., Persikov, Anton V., Dagher, Hayat, Dalgleish, Raymond, Jensen, Shane T., Jeunemaitre, Xavier, Savige, Judy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509119/ https://www.ncbi.nlm.nih.gov/pubmed/28704418 http://dx.doi.org/10.1371/journal.pone.0175582 |
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