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Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study

OBJECTIVE: We performed single-variant and gene-based association analyses of plasma amyloid-β (aβ) concentrations using whole exome sequence from 1,414 African and European Americans. Our goal was to identify genes that influence plasma aβ(42) concentrations and aβ(42):aβ(40) ratios in late middle...

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Detalles Bibliográficos
Autores principales:	Simino, Jeannette, Wang, Zhiying, Bressler, Jan, Chouraki, Vincent, Yang, Qiong, Younkin, Steven G., Seshadri, Sudha, Fornage, Myriam, Boerwinkle, Eric, Mosley, Thomas H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509141/ https://www.ncbi.nlm.nih.gov/pubmed/28704393 http://dx.doi.org/10.1371/journal.pone.0180046

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