RNA secondary structure and nucleotide composition of the conserved hallmark sequence of Leishmania SIDER2 retroposons are essential for endonucleolytic cleavage and mRNA degradation

We have reported previously that Short Interspersed Degenerate Retroposons of the SIDER2 subfamily, largely located within 3'UTRs of Leishmania transcripts, promote rapid turnover of mRNAs through endonucleolytic cleavage within the highly conserved second tandem 79-nt hallmark sequence (79-nt...

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Detalles Bibliográficos
Autores principales: Azizi, Hiva, Romão, Tatiany P., Santos Charret, Karen, Padmanabhan, Prasad K., de Melo Neto, Osvaldo P., Müller-McNicoll, Michaela, Papadopoulou, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509151/
https://www.ncbi.nlm.nih.gov/pubmed/28704426
http://dx.doi.org/10.1371/journal.pone.0180678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509151/
https://www.ncbi.nlm.nih.gov/pubmed/28704426
http://dx.doi.org/10.1371/journal.pone.0180678

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