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Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts

Lower urinary tract symptoms (LUTS) are highly prevalent in the aging population, particularly in men. Historically, prostate enlargement was thought to be responsible for most cases of male LUTS. Several risk factors for the development of benign prostate enlargement/hyperplasia (BPE/BPH) have been...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Ling, Kuo, Hann-Chorng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509197/
https://www.ncbi.nlm.nih.gov/pubmed/28757771
http://dx.doi.org/10.4103/tcmj.tcmj_20_17
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author Lee, Cheng-Ling
Kuo, Hann-Chorng
author_facet Lee, Cheng-Ling
Kuo, Hann-Chorng
author_sort Lee, Cheng-Ling
collection PubMed
description Lower urinary tract symptoms (LUTS) are highly prevalent in the aging population, particularly in men. Historically, prostate enlargement was thought to be responsible for most cases of male LUTS. Several risk factors for the development of benign prostate enlargement/hyperplasia (BPE/BPH) have been identified, including age, genetics, hormones, growth factors, inflammation, and lifestyle factors. However, as our knowledge continues to evolve, male LUTS are no longer managed entirely in a prostate-centric fashion. In this article, we review current concepts in the epidemiology, etiology, and pathophysiology of BPE/BPH and male LUTS.
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spelling pubmed-55091972017-07-26 Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts Lee, Cheng-Ling Kuo, Hann-Chorng Tzu Chi Med J Review Article Lower urinary tract symptoms (LUTS) are highly prevalent in the aging population, particularly in men. Historically, prostate enlargement was thought to be responsible for most cases of male LUTS. Several risk factors for the development of benign prostate enlargement/hyperplasia (BPE/BPH) have been identified, including age, genetics, hormones, growth factors, inflammation, and lifestyle factors. However, as our knowledge continues to evolve, male LUTS are no longer managed entirely in a prostate-centric fashion. In this article, we review current concepts in the epidemiology, etiology, and pathophysiology of BPE/BPH and male LUTS. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5509197/ /pubmed/28757771 http://dx.doi.org/10.4103/tcmj.tcmj_20_17 Text en Copyright: © 2017 Tzu Chi Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Lee, Cheng-Ling
Kuo, Hann-Chorng
Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts
title Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts
title_full Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts
title_fullStr Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts
title_full_unstemmed Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts
title_short Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts
title_sort pathophysiology of benign prostate enlargement and lower urinary tract symptoms: current concepts
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509197/
https://www.ncbi.nlm.nih.gov/pubmed/28757771
http://dx.doi.org/10.4103/tcmj.tcmj_20_17
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