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Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts
Lower urinary tract symptoms (LUTS) are highly prevalent in the aging population, particularly in men. Historically, prostate enlargement was thought to be responsible for most cases of male LUTS. Several risk factors for the development of benign prostate enlargement/hyperplasia (BPE/BPH) have been...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509197/ https://www.ncbi.nlm.nih.gov/pubmed/28757771 http://dx.doi.org/10.4103/tcmj.tcmj_20_17 |
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author | Lee, Cheng-Ling Kuo, Hann-Chorng |
author_facet | Lee, Cheng-Ling Kuo, Hann-Chorng |
author_sort | Lee, Cheng-Ling |
collection | PubMed |
description | Lower urinary tract symptoms (LUTS) are highly prevalent in the aging population, particularly in men. Historically, prostate enlargement was thought to be responsible for most cases of male LUTS. Several risk factors for the development of benign prostate enlargement/hyperplasia (BPE/BPH) have been identified, including age, genetics, hormones, growth factors, inflammation, and lifestyle factors. However, as our knowledge continues to evolve, male LUTS are no longer managed entirely in a prostate-centric fashion. In this article, we review current concepts in the epidemiology, etiology, and pathophysiology of BPE/BPH and male LUTS. |
format | Online Article Text |
id | pubmed-5509197 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-55091972017-07-26 Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts Lee, Cheng-Ling Kuo, Hann-Chorng Tzu Chi Med J Review Article Lower urinary tract symptoms (LUTS) are highly prevalent in the aging population, particularly in men. Historically, prostate enlargement was thought to be responsible for most cases of male LUTS. Several risk factors for the development of benign prostate enlargement/hyperplasia (BPE/BPH) have been identified, including age, genetics, hormones, growth factors, inflammation, and lifestyle factors. However, as our knowledge continues to evolve, male LUTS are no longer managed entirely in a prostate-centric fashion. In this article, we review current concepts in the epidemiology, etiology, and pathophysiology of BPE/BPH and male LUTS. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5509197/ /pubmed/28757771 http://dx.doi.org/10.4103/tcmj.tcmj_20_17 Text en Copyright: © 2017 Tzu Chi Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Lee, Cheng-Ling Kuo, Hann-Chorng Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts |
title | Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts |
title_full | Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts |
title_fullStr | Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts |
title_full_unstemmed | Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts |
title_short | Pathophysiology of benign prostate enlargement and lower urinary tract symptoms: Current concepts |
title_sort | pathophysiology of benign prostate enlargement and lower urinary tract symptoms: current concepts |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509197/ https://www.ncbi.nlm.nih.gov/pubmed/28757771 http://dx.doi.org/10.4103/tcmj.tcmj_20_17 |
work_keys_str_mv | AT leechengling pathophysiologyofbenignprostateenlargementandlowerurinarytractsymptomscurrentconcepts AT kuohannchorng pathophysiologyofbenignprostateenlargementandlowerurinarytractsymptomscurrentconcepts |