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IL-13 is a central mediator of chemical-induced airway hyperreactivity in mice

BACKGROUND: While the importance of the Th2 cytokine IL-13 as a central mediator of airway hyperreactivity (AHR) has been described in allergic protein-induced asthma, this has never been investigated in chemical-induced asthma. OBJECTIVE: We examined the importance of IL-13 in a mouse model of chem...

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Detalles Bibliográficos
Autores principales:	Devos, Fien C., Pollaris, Lore, Cremer, Jonathan, Seys, Sven, Hoshino, Tomoaki, Ceuppens, Jan, Talavera, Karel, Nemery, Benoit, Hoet, Peter H. M., Vanoirbeek, Jeroen A. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509233/ https://www.ncbi.nlm.nih.gov/pubmed/28704401 http://dx.doi.org/10.1371/journal.pone.0180690

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