Reduced susceptibility of clinical strains of Mycobacterium tuberculosis to reactive nitrogen species promotes survival in activated macrophages

BACKGROUND: Drugs such as isoniazid (INH) and pretomanid (PRT), used against Mycobacterium tuberculosis are active partly through generation of reactive nitrogen species (RNS). The aim of this study was to explore variability in intracellular susceptibility to nitric oxide (NO) in clinical strains o...

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Detalles Bibliográficos
Autores principales: Idh, Jonna, Andersson, Blanka, Lerm, Maria, Raffetseder, Johanna, Eklund, Daniel, Woksepp, Hanna, Werngren, Jim, Mansjö, Mikael, Sundqvist, Tommy, Stendahl, Olle, Schön, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509328/
https://www.ncbi.nlm.nih.gov/pubmed/28704501
http://dx.doi.org/10.1371/journal.pone.0181221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509328/
https://www.ncbi.nlm.nih.gov/pubmed/28704501
http://dx.doi.org/10.1371/journal.pone.0181221

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