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Substrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone Sse1 is not obligate for its biological activities

The highly conserved heat shock protein 70 (Hsp70) is a ubiquitous molecular chaperone essential for maintaining cellular protein homeostasis. The related protein Hsp110 (Sse1/Sse2 in Saccharomyces cerevisiae) functions as a nucleotide exchange factor (NEF) to regulate the protein folding activity o...

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Detalles Bibliográficos
Autores principales:	Garcia, Veronica M., Nillegoda, Nadinath B., Bukau, Bernd, Morano, Kevin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509420/ https://www.ncbi.nlm.nih.gov/pubmed/28539411 http://dx.doi.org/10.1091/mbc.E17-01-0070

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