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Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress
Aging is commonly associated with chronic low-grade inflammation and hypertension but it is unknown whether a cause-effect relationship exists between them. We compared the sensitivity of young adult (8-12 w) and aged (23-31 mo) male C57Bl6J mice to develop hypertension in response to a slow-pressor...
Autores principales: | Dinh, Quynh Nhu, Drummond, Grant R., Kemp-Harper, Barbara K., Diep, Henry, Silva, T. Michael De, Kim, Hyun Ah, Vinh, Antony, Robertson, Avril A.B., Cooper, Matthew A., Mansell, Ashley, Chrissobolis, Sophocles, Sobey, Christopher G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509458/ https://www.ncbi.nlm.nih.gov/pubmed/28659507 http://dx.doi.org/10.18632/aging.101255 |
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