Elimination of undifferentiated human embryonic stem cells by cardiac glycosides

An important safety concern in the use of human pluripotent stem cells (hPSCs) is tumorigenic risk, because these cells can form teratomas after an in vivo injection at ectopic sites. Several thousands of undifferentiated hPSCs are sufficient to induce teratomas in a mouse model. Thus, it is critica...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Tsen, Wang, Cheng-Kai, Yang, Shang-Chih, Hsu, Shu-Ching, Lin, Hsuan, Chang, Fang-Pei, Kuo, Tzu-Chien, Shen, Chia-Ning, Chiang, Po-Ming, Hsiao, Michael, Lu, Frank Leigh, Lu, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509667/
https://www.ncbi.nlm.nih.gov/pubmed/28706279
http://dx.doi.org/10.1038/s41598-017-05616-2

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