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Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation
The Bcl-2 proteins form a complex interaction network that controls mitochondrial permeabilization and apoptosis. The relative importance of different Bcl-2 complexes and their spatio-temporal regulation is debated. Using fluorescence cross-correlation spectroscopy to quantify the interactions withi...
Autores principales: | Bleicken, Stephanie, Hantusch, Annika, Das, Kushal Kumar, Frickey, Tancred, Garcia-Saez, Ana J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509671/ https://www.ncbi.nlm.nih.gov/pubmed/28706229 http://dx.doi.org/10.1038/s41467-017-00086-6 |
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