Cargando…

Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation

The Bcl-2 proteins form a complex interaction network that controls mitochondrial permeabilization and apoptosis. The relative importance of different Bcl-2 complexes and their spatio-temporal regulation is debated. Using fluorescence cross-correlation spectroscopy to quantify the interactions withi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bleicken, Stephanie, Hantusch, Annika, Das, Kushal Kumar, Frickey, Tancred, Garcia-Saez, Ana J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509671/
https://www.ncbi.nlm.nih.gov/pubmed/28706229
http://dx.doi.org/10.1038/s41467-017-00086-6

Ejemplares similares