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Polydextrose changes the gut microbiome and attenuates fasting triglyceride and cholesterol levels in Western diet fed mice
Obesity and dyslipidemia are hallmarks of metabolic and cardiovascular diseases. Polydextrose (PDX), a soluble fiber has lipid lowering effects. We hypothesize that PDX reduces triglycerides and cholesterol by influencing gut microbiota, which in turn modulate intestinal gene expression. C57BL/6 mal...
Autores principales: | Raza, Ghulam Shere, Putaala, Heli, Hibberd, Ashley A., Alhoniemi, Esa, Tiihonen, Kirsti, Mäkelä, Kari Antero, Herzig, Karl-Heinz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509720/ https://www.ncbi.nlm.nih.gov/pubmed/28706193 http://dx.doi.org/10.1038/s41598-017-05259-3 |
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