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DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia

The morphogenic factor Sonic hedgehog (Shh) signals through the primary cilium, which relies on intraflagellar transport to maintain its structural integrity and function. However, the process by which protein and lipid cargos are delivered to the primary cilium from their sites of synthesis still r...

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Detalles Bibliográficos
Autores principales: Ding, Jie, Shao, Lei, Yao, Yixing, Tong, Xin, Liu, Huaize, Yue, Shen, Xie, Lu, Cheng, Steven Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509727/
https://www.ncbi.nlm.nih.gov/pubmed/28706295
http://dx.doi.org/10.1038/s41598-017-05680-8