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Investigation of brain tissue infiltration by medulloblastoma cells in an ex vivo model

Medulloblastoma (MB) is a paediatric cancer of the cerebellum that can develop cerebellar and leptomeningeal metastases. Local brain tissue infiltration, the underlying cause of metastasis and relapse, remains unexplored. We developed a novel approach to investigate tissue infiltration of MB using o...

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Detalles Bibliográficos
Autores principales: Neve, Anuja, Santhana Kumar, Karthiga, Tripolitsioti, Dimitra, Grotzer, Michael A., Baumgartner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509741/
https://www.ncbi.nlm.nih.gov/pubmed/28706234
http://dx.doi.org/10.1038/s41598-017-05573-w