Genomic Signature of the Natural Oncolytic Herpes Simplex Virus HF10 and Its Therapeutic Role in Preclinical and Clinical Trials

Oncolytic viruses (OVs) are opening new possibilities in cancer therapy with their unique mechanism of selective replication within tumor cells and triggering of antitumor immune responses. HF10 is an oncolytic herpes simplex virus-1 with a unique genomic structure that has non-engineered deletions...

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Detalles Bibliográficos
Autores principales: Eissa, Ibrahim Ragab, Naoe, Yoshinori, Bustos-Villalobos, Itzel, Ichinose, Toru, Tanaka, Maki, Zhiwen, Wu, Mukoyama, Nobuaki, Morimoto, Taishi, Miyajima, Noriyuki, Hitoki, Hasegawa, Sumigama, Seiji, Aleksic, Branko, Kodera, Yasuhiro, Kasuya, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509757/
https://www.ncbi.nlm.nih.gov/pubmed/28770166
http://dx.doi.org/10.3389/fonc.2017.00149

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