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Nature nurtures the design of new semi-synthetic macrolide antibiotics

Erythromycin and its analogs are used to treat respiratory tract and other infections. The broad use of these antibiotics during the last 5 decades has led to resistance that can range from 20% to over 70% in certain parts of the world. Efforts to find macrolides that were active against macrolide-r...

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Detalles Bibliográficos
Autores principales: Fernandes, Prabhavathi, Martens, Evan, Pereira, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509991/
https://www.ncbi.nlm.nih.gov/pubmed/27899792
http://dx.doi.org/10.1038/ja.2016.137