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A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE‐3
AIM: The aim of the present study was to investigate whether increasing the bosentan dosing frequency from 2 mg kg(–1) twice daily (b.i.d.) to 2 mg kg(–1) three times daily (t.i.d.) in children with pulmonary arterial hypertension (PAH) (from ≥3 months to <12 years of age) would increase exposure...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510076/ https://www.ncbi.nlm.nih.gov/pubmed/28213957 http://dx.doi.org/10.1111/bcp.13267 |