Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

High-affinity antibody production through the germinal centre (GC) response is a pivotal process in adaptive immunity. Abnormal development of follicular helper T (T(FH)) cells can induce the GC response to self-antigens, subsequently leading to autoimmunity. Here we show the transcriptional repress...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Sungjun, Lee, Seungwon, Lee, Choong-Gu, Park, Guk Yeol, Hong, Hyebeen, Lee, Jeon-Soo, Kim, Young Min, Lee, Sung Bae, Hwang, Daehee, Choi, Youn Soo, Fryer, John D., Im, Sin-Hyeog, Lee, Seung-Woo, Lee, Yoontae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510180/
https://www.ncbi.nlm.nih.gov/pubmed/28855737
http://dx.doi.org/10.1038/ncomms16037

Ejemplares similares

Ejemplares similares