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Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets

The decreasing cost of genomic technologies has enabled the molecular characterization of large-scale clinical disease samples and of molecular changes upon drug treatment in various disease models. Exploring methods to relate diseases to potentially efficacious drugs through various molecular featu...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Ma, Li, Paik, Hyojung, Sirota, Marina, Wei, Wei, Chua, Mei-Sze, So, Samuel, Butte, Atul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510182/
https://www.ncbi.nlm.nih.gov/pubmed/28699633
http://dx.doi.org/10.1038/ncomms16022