Cargando…
Changes in Ionic Conductance Signature of Nociceptive Neurons Underlying Fabry Disease Phenotype
The first symptom arising in many Fabry patients is neuropathic pain due to changes in small myelinated and unmyelinated fibers in the periphery, which is subsequently followed by a loss of sensory perception. Here we studied changes in the peripheral nervous system of Fabry patients and a Fabry mou...
Autores principales: | Namer, Barbara, Ørstavik, Kirstin, Schmidt, Roland, Mair, Norbert, Kleggetveit, Inge Petter, Zeidler, Maximillian, Martha, Theresa, Jorum, Ellen, Schmelz, Martin, Kalpachidou, Theodora, Kress, Michaela, Langeslag, Michiel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510289/ https://www.ncbi.nlm.nih.gov/pubmed/28769867 http://dx.doi.org/10.3389/fneur.2017.00335 |
Ejemplares similares
-
Signatures of Altered Gene Expression in Dorsal Root Ganglia of a Fabry Disease Mouse Model
por: Kummer, Kai K., et al.
Publicado: (2018) -
Altered Gene Expression in Prefrontal Cortex of a Fabry Disease Mouse Model
por: Kummer, Kai K., et al.
Publicado: (2018) -
Impaired mechanical, heat, and cold nociception in a murine model of genetic TACE/ADAM17 knockdown
por: Quarta, Serena, et al.
Publicado: (2019) -
Pathological nociceptors in two patients with erythromelalgia‐like symptoms and rare genetic Nav 1.9 variants
por: Kleggetveit, Inge P., et al.
Publicado: (2016) -
Sphingosine 1-phosphate to p38 signaling via S1P(1) receptor and Gαi/o evokes augmentation of capsaicin-induced ionic currents in mouse sensory neurons
por: Langeslag, Michiel, et al.
Publicado: (2014)