Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy

Metronidazole-induced neuro-toxicity, though rare, is known. A characteristic spatial distribution of lesions in cerebellar dentate nuclei and dorsal pons is known. However, temporal progression of lesions on magnetic resonance imaging (MRI) has not been described previously. We describe two such ca...

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Detalles Bibliográficos
Autores principales: Singh, Rupinder, Kaur, Ramanjeet, Pokhariyal, Pawan, Aggarwal, Rajul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Neuroradiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510308/
https://www.ncbi.nlm.nih.gov/pubmed/28744071
http://dx.doi.org/10.4103/ijri.IJRI_341_16
Descripción
Sumario:Metronidazole-induced neuro-toxicity, though rare, is known. A characteristic spatial distribution of lesions in cerebellar dentate nuclei and dorsal pons is known. However, temporal progression of lesions on magnetic resonance imaging (MRI) has not been described previously. We describe two such cases which presented initially with splenial hyperintesity and showed progression to characterstic lesions. Both cases improved with stoppage of metronidazole.

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