Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy

Metronidazole-induced neuro-toxicity, though rare, is known. A characteristic spatial distribution of lesions in cerebellar dentate nuclei and dorsal pons is known. However, temporal progression of lesions on magnetic resonance imaging (MRI) has not been described previously. We describe two such ca...

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Autores principales: Singh, Rupinder, Kaur, Ramanjeet, Pokhariyal, Pawan, Aggarwal, Rajul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Neuroradiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510308/
https://www.ncbi.nlm.nih.gov/pubmed/28744071
http://dx.doi.org/10.4103/ijri.IJRI_341_16
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author Singh, Rupinder
Kaur, Ramanjeet
Pokhariyal, Pawan
Aggarwal, Rajul
author_facet Singh, Rupinder
Kaur, Ramanjeet
Pokhariyal, Pawan
Aggarwal, Rajul
author_sort Singh, Rupinder
collection PubMed
description Metronidazole-induced neuro-toxicity, though rare, is known. A characteristic spatial distribution of lesions in cerebellar dentate nuclei and dorsal pons is known. However, temporal progression of lesions on magnetic resonance imaging (MRI) has not been described previously. We describe two such cases which presented initially with splenial hyperintesity and showed progression to characterstic lesions. Both cases improved with stoppage of metronidazole.
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spelling pubmed-55103082017-07-25 Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy Singh, Rupinder Kaur, Ramanjeet Pokhariyal, Pawan Aggarwal, Rajul Indian J Radiol Imaging Neuroradiology Metronidazole-induced neuro-toxicity, though rare, is known. A characteristic spatial distribution of lesions in cerebellar dentate nuclei and dorsal pons is known. However, temporal progression of lesions on magnetic resonance imaging (MRI) has not been described previously. We describe two such cases which presented initially with splenial hyperintesity and showed progression to characterstic lesions. Both cases improved with stoppage of metronidazole. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5510308/ /pubmed/28744071 http://dx.doi.org/10.4103/ijri.IJRI_341_16 Text en Copyright: © 2017 Indian Journal of Radiology and Imaging http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Neuroradiology
Singh, Rupinder
Kaur, Ramanjeet
Pokhariyal, Pawan
Aggarwal, Rajul
Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy
title Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy
title_full Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy
title_fullStr Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy
title_full_unstemmed Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy
title_short Sequential MR imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy
title_sort sequential mr imaging (with diffusion-weighted imaging) changes in metronidazole-induced encephalopathy
topic Neuroradiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510308/
https://www.ncbi.nlm.nih.gov/pubmed/28744071
http://dx.doi.org/10.4103/ijri.IJRI_341_16
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AT pokhariyalpawan sequentialmrimagingwithdiffusionweightedimagingchangesinmetronidazoleinducedencephalopathy
AT aggarwalrajul sequentialmrimagingwithdiffusionweightedimagingchangesinmetronidazoleinducedencephalopathy

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