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Palmitate and oleate exert differential effects on insulin signalling and glucose uptake in human skeletal muscle cells

Saturated fatty acids are implicated in the development of insulin resistance, whereas unsaturated fatty acids may have a protective effect on metabolism. We tested in primary human myotubes if insulin resistance induced by saturated fatty acid palmitate can be ameliorated by concomitant exposure to...

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Detalles Bibliográficos
Autores principales: Mäkinen, Selina, Nguyen, Yen H, Skrobuk, Paulina, Koistinen, Heikki A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510447/
https://www.ncbi.nlm.nih.gov/pubmed/28584168
http://dx.doi.org/10.1530/EC-17-0039