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Elevated tumor mutational burden and prolonged clinical response to anti-PD-L1 antibody in platinum-resistant recurrent ovarian cancer
• We report an ovarian cancer patient with a prolonged response to immunotherapy. • Comprehensive genomic profiling may detect patients who benefit from immunotherapy. • Mutational burden thresholds for ovarian cancer may be lower than other cancers.
Autores principales: | Morse, Christopher B., Elvin, Julia A., Gay, Laurie M., Liao, John B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510487/ https://www.ncbi.nlm.nih.gov/pubmed/28736741 http://dx.doi.org/10.1016/j.gore.2017.06.013 |
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