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PCSK9 inhibitors – from discovery of a single mutation to a groundbreaking therapy of lipid disorders in one decade

Hypercholesterolemia is one of the main risk factors for coronary heart disease and significantly contributes to the high mortality associated with cardiovascular diseases. Statin therapy represents the gold standard in the reduction of low-density lipoprotein cholesterol concentration. Nevertheless...

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Detalles Bibliográficos
Autores principales: Jaworski, Krzysztof, Jankowski, Piotr, Kosior, Dariusz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510512/
https://www.ncbi.nlm.nih.gov/pubmed/28721159
http://dx.doi.org/10.5114/aoms.2017.65239