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Detection of 5-methylcytosine and 5-hydroxymethylcytosine in DNA via host–guest interactions inside α-hemolysin nanopores

Cytosine methylation and hydroxymethylation are both important epigenetic modifications of DNA in mammalian cells. Therefore, profiling DNA (hydroxy)methylation across the genome is vital for understanding their roles in gene regulation. Here, we report a nanopore-based approach for quick and reliab...

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Detalles Bibliográficos
Autores principales:	Zeng, Tao, Liu, Lei, Li, Ting, Li, Yuru, Gao, Juan, Zhao, Yuliang, Wu, Hai-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510575/ https://www.ncbi.nlm.nih.gov/pubmed/28757950 http://dx.doi.org/10.1039/c5sc01436k

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