Mesenchymal Stem Cell Migration and Proliferation Are Mediated by Hypoxia-Inducible Factor-1α Upstream of Notch and SUMO Pathways

Mesenchymal stem cells (MSCs) are effective in treating several pathologies. We and others have demonstrated that hypoxia or hypoxia-inducible factor 1 alpha (HIF-1α) stabilization improves several MSC functions, including cell adhesion, migration, and proliferation, thereby increasing their therape...

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Detalles Bibliográficos
Autores principales: Ciria, María, García, Nahuel A., Ontoria-Oviedo, Imelda, González-King, Hernán, Carrero, Rubén, De La Pompa, José Luis, Montero, José Anastasio, Sepúlveda, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Original Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510679/
https://www.ncbi.nlm.nih.gov/pubmed/28520516
http://dx.doi.org/10.1089/scd.2016.0331

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