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H3F3A (Histone 3.3) G34W Immunohistochemistry: A Reliable Marker Defining Benign and Malignant Giant Cell Tumor of Bone

Giant cell tumor of bone (GCTB) is a locally aggressive subarticular tumor. Having recently reported that H3.3 G34W mutations are characteristic of this tumor type, we have now investigated the sensitivity and specificity of the anti-histone H3.3 G34W rabbit monoclonal antibody in a wide variety of...

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Detalles Bibliográficos
Autores principales: Amary, Fernanda, Berisha, Fitim, Ye, Hongtao, Gupta, Manu, Gutteridge, Alice, Baumhoer, Daniel, Gibbons, Rebecca, Tirabosco, Roberto, O’Donnell, Paul, Flanagan, Adrienne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health, Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510691/
https://www.ncbi.nlm.nih.gov/pubmed/28505000
http://dx.doi.org/10.1097/PAS.0000000000000859

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