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A new and potentially prebiotic α-cytidine derivative
A new α-cytidine derivative was synthesised from the prebiotic reaction of ribose aminooxazoline and dicyanoacetylene. The tetracyclic structure of the product was confirmed by X-ray diffraction and then an alternative 6-step synthetic pathway to the product was found which was suitable for large-sc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510716/ https://www.ncbi.nlm.nih.gov/pubmed/28229150 http://dx.doi.org/10.1039/c7cc00693d |
| _version_ | 1783250218860412928 |
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| author | Tsanakopoulou, Maria Xu, Jianfeng Bond, Andrew D. Sutherland, John D. |
| author_facet | Tsanakopoulou, Maria Xu, Jianfeng Bond, Andrew D. Sutherland, John D. |
| author_sort | Tsanakopoulou, Maria |
| collection | PubMed |
| description | A new α-cytidine derivative was synthesised from the prebiotic reaction of ribose aminooxazoline and dicyanoacetylene. The tetracyclic structure of the product was confirmed by X-ray diffraction and then an alternative 6-step synthetic pathway to the product was found which was suitable for large-scale synthesis. |
| format | Online Article Text |
| id | pubmed-5510716 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Royal Society of Chemistry |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-55107162017-07-14 A new and potentially prebiotic α-cytidine derivative Tsanakopoulou, Maria Xu, Jianfeng Bond, Andrew D. Sutherland, John D. Chem Commun (Camb) Chemistry A new α-cytidine derivative was synthesised from the prebiotic reaction of ribose aminooxazoline and dicyanoacetylene. The tetracyclic structure of the product was confirmed by X-ray diffraction and then an alternative 6-step synthetic pathway to the product was found which was suitable for large-scale synthesis. Royal Society of Chemistry 2017-03-21 2017-02-23 /pmc/articles/PMC5510716/ /pubmed/28229150 http://dx.doi.org/10.1039/c7cc00693d Text en This journal is © The Royal Society of Chemistry 2017 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Chemistry Tsanakopoulou, Maria Xu, Jianfeng Bond, Andrew D. Sutherland, John D. A new and potentially prebiotic α-cytidine derivative |
| title | A new and potentially prebiotic α-cytidine derivative
|
| title_full | A new and potentially prebiotic α-cytidine derivative
|
| title_fullStr | A new and potentially prebiotic α-cytidine derivative
|
| title_full_unstemmed | A new and potentially prebiotic α-cytidine derivative
|
| title_short | A new and potentially prebiotic α-cytidine derivative
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| title_sort | new and potentially prebiotic α-cytidine derivative |
| topic | Chemistry |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510716/ https://www.ncbi.nlm.nih.gov/pubmed/28229150 http://dx.doi.org/10.1039/c7cc00693d |
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