The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands

HLA-B(∗)46:01 was formed by an intergenic mini-conversion, between HLA-B(∗)15:01 and HLA-C(∗)01:02, in Southeast Asia during the last 50,000 years, and it has since become the most common HLA-B allele in the region. A functional effect of the mini-conversion was introduction of the C1 epitope into H...

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Detalles Bibliográficos
Autores principales: Hilton, Hugo G., McMurtrey, Curtis P., Han, Alex S., Djaoud, Zakia, Guethlein, Lisbeth A., Blokhuis, Jeroen H., Pugh, Jason L., Goyos, Ana, Horowitz, Amir, Buchli, Rico, Jackson, Ken W., Bardet, Wilfred, Bushnell, David A., Robinson, Philip J., Mendoza, Juan L., Birnbaum, Michael E., Nielsen, Morten, Garcia, K. Christopher, Hildebrand, William H., Parham, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510751/
https://www.ncbi.nlm.nih.gov/pubmed/28514659
http://dx.doi.org/10.1016/j.celrep.2017.04.059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510751/
https://www.ncbi.nlm.nih.gov/pubmed/28514659
http://dx.doi.org/10.1016/j.celrep.2017.04.059

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