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Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis

Infection of weanling C57BL/6 mice with the TE strain of Sindbis virus (SINV) causes nonfatal encephalomyelitis associated with hippocampal-based memory impairment that is partially prevented by treatment with 6-diazo-5-oxo-l-norleucine (DON), a glutamine antagonist (Potter et al., J Neurovirol 21:1...

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Detalles Bibliográficos
Autores principales:	Baxter, Victoria K., Glowinski, Rebecca, Braxton, Alicia M., Potter, Michelle C., Slusher, Barbara S., Griffin, Diane E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510753/ https://www.ncbi.nlm.nih.gov/pubmed/28531865 http://dx.doi.org/10.1016/j.virol.2017.05.013

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