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Expansion and Purification Are Critical for the Therapeutic Application of Pluripotent Stem Cell-Derived Myogenic Progenitors
Recent reports have documented the differentiation of human pluripotent stem cells toward the skeletal myogenic lineage using transgene- and cell purification-free approaches. Although these protocols generate myocytes, they have not demonstrated scalability, safety, and in vivo engraftment, which a...
Autores principales: | Kim, Jaemin, Magli, Alessandro, Chan, Sunny S.K., Oliveira, Vanessa K.P., Wu, Jianbo, Darabi, Radbod, Kyba, Michael, Perlingeiro, Rita C.R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511038/ https://www.ncbi.nlm.nih.gov/pubmed/28528701 http://dx.doi.org/10.1016/j.stemcr.2017.04.022 |
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