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Expansion and Purification Are Critical for the Therapeutic Application of Pluripotent Stem Cell-Derived Myogenic Progenitors

Recent reports have documented the differentiation of human pluripotent stem cells toward the skeletal myogenic lineage using transgene- and cell purification-free approaches. Although these protocols generate myocytes, they have not demonstrated scalability, safety, and in vivo engraftment, which a...

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Detalles Bibliográficos
Autores principales: Kim, Jaemin, Magli, Alessandro, Chan, Sunny S.K., Oliveira, Vanessa K.P., Wu, Jianbo, Darabi, Radbod, Kyba, Michael, Perlingeiro, Rita C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511038/
https://www.ncbi.nlm.nih.gov/pubmed/28528701
http://dx.doi.org/10.1016/j.stemcr.2017.04.022

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