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The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue
Age-related macular degeneration (AMD) is a common cause of central visual loss in the elderly. Retinal pigment epithelial (RPE) cell loss occurs early in the course of AMD and RPE cell transplantation holds promise to slow disease progression. We report that subretinal transplantation of RPE stem c...
Autores principales: | Davis, Richard J., Alam, Nazia M., Zhao, Cuiping, Müller, Claudia, Saini, Janmeet S., Blenkinsop, Timothy A., Mazzoni, Francesca, Campbell, Melissa, Borden, Susan M., Charniga, Carol J., Lederman, Patty L., Aguilar, Vanessa, Naimark, Michael, Fiske, Michael, Boles, Nathan, Temple, Sally, Finnemann, Silvia C., Prusky, Glen T., Stern, Jeffrey H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511099/ https://www.ncbi.nlm.nih.gov/pubmed/28625537 http://dx.doi.org/10.1016/j.stemcr.2017.05.016 |
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