NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin

NEK family kinases are serine/threonine kinases that have been functionally implicated in the regulation of the disjunction of the centrosome, the assembly of the mitotic spindle, the function of the primary cilium and the DNA damage response. NEK1 shows pleiotropic functions and has been found to b...

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Detalles Bibliográficos
Autores principales: Melo-Hanchuk, Talita D., Slepicka, Priscila Ferreira, Meirelles, Gabriela Vaz, Basei, Fernanda Luisa, Lovato, Diogo Ventura, Granato, Daniela Campos, Pauletti, Bianca Alves, Domingues, Romenia Ramos, Leme, Adriana Franco Paes, Pelegrini, Alessandra Luiza, Lenz, Guido, Knapp, Stefan, Elkins, Jonathan M., Kobarg, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511132/
https://www.ncbi.nlm.nih.gov/pubmed/28710492
http://dx.doi.org/10.1038/s41598-017-05325-w

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