Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter

Dopamine transporter (DAT) has been shown to accumulate in filopodia in neurons and non-neuronal cells. To examine the mechanisms of DAT filopodial targeting, we used quantitative live-cell fluorescence microscopy, and compared the effects of the DAT inhibitor cocaine and its fluorescent analog JHC1...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Shiqi, Cheng, Mary H., Guthrie, Daryl A., Newman, Amy H., Bahar, Ivet, Sorkin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511133/
https://www.ncbi.nlm.nih.gov/pubmed/28710426
http://dx.doi.org/10.1038/s41598-017-05637-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511133/
https://www.ncbi.nlm.nih.gov/pubmed/28710426
http://dx.doi.org/10.1038/s41598-017-05637-x

Ejemplares similares