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Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter

Dopamine transporter (DAT) has been shown to accumulate in filopodia in neurons and non-neuronal cells. To examine the mechanisms of DAT filopodial targeting, we used quantitative live-cell fluorescence microscopy, and compared the effects of the DAT inhibitor cocaine and its fluorescent analog JHC1...

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Detalles Bibliográficos
Autores principales:	Ma, Shiqi, Cheng, Mary H., Guthrie, Daryl A., Newman, Amy H., Bahar, Ivet, Sorkin, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511133/ https://www.ncbi.nlm.nih.gov/pubmed/28710426 http://dx.doi.org/10.1038/s41598-017-05637-x

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