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Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer

Biodegradable and physically transient optics represent an emerging paradigm in healthcare devices by harnessing optically active system and obviating issues with chronic uses. Light emitting components that can efficiently interact with their environments have advantages of high sensitivity, visibi...

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Detalles Bibliográficos
Autores principales: Min, Kyungtaek, Kim, Sookyoung, Kim, Chang Gun, Kim, Sunghwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511142/
https://www.ncbi.nlm.nih.gov/pubmed/28710484
http://dx.doi.org/10.1038/s41598-017-05842-8
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author Min, Kyungtaek
Kim, Sookyoung
Kim, Chang Gun
Kim, Sunghwan
author_facet Min, Kyungtaek
Kim, Sookyoung
Kim, Chang Gun
Kim, Sunghwan
author_sort Min, Kyungtaek
collection PubMed
description Biodegradable and physically transient optics represent an emerging paradigm in healthcare devices by harnessing optically active system and obviating issues with chronic uses. Light emitting components that can efficiently interact with their environments have advantages of high sensitivity, visibility, and wireless operation. Here, we report a novel combination of silk biopolymer and optically active organic dyes resulting in versatile fluorescent silk nanofibers (FSNs). FSNs generated by the electrospinning method exhibit attractive functions of the doped organic dyes along with programming the system that physically disappear at prescribed time. Red-green-blue (RGB) fluorescent nanofibrous mats, eco-friendly and transient fluorescent chemosensors for acid vapor detection, and disposable membranes for nutrition delivery were successfully demonstrated using FSNs. These functions introduced using four water soluble dyes: rhodamine B, sodium fluorescein, stilbene 420, and riboflavin. The FSN with sodium fluorescein especially, showed a sensing capability for hazardous and volatile hydrochloric acid vapors. Delivering riboflavin (vitamin B(2), an important nutrient for skin care) in the FSN to a biological tissue could be observed by tracing the fluorescence of riboflavin.
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spelling pubmed-55111422017-07-17 Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer Min, Kyungtaek Kim, Sookyoung Kim, Chang Gun Kim, Sunghwan Sci Rep Article Biodegradable and physically transient optics represent an emerging paradigm in healthcare devices by harnessing optically active system and obviating issues with chronic uses. Light emitting components that can efficiently interact with their environments have advantages of high sensitivity, visibility, and wireless operation. Here, we report a novel combination of silk biopolymer and optically active organic dyes resulting in versatile fluorescent silk nanofibers (FSNs). FSNs generated by the electrospinning method exhibit attractive functions of the doped organic dyes along with programming the system that physically disappear at prescribed time. Red-green-blue (RGB) fluorescent nanofibrous mats, eco-friendly and transient fluorescent chemosensors for acid vapor detection, and disposable membranes for nutrition delivery were successfully demonstrated using FSNs. These functions introduced using four water soluble dyes: rhodamine B, sodium fluorescein, stilbene 420, and riboflavin. The FSN with sodium fluorescein especially, showed a sensing capability for hazardous and volatile hydrochloric acid vapors. Delivering riboflavin (vitamin B(2), an important nutrient for skin care) in the FSN to a biological tissue could be observed by tracing the fluorescence of riboflavin. Nature Publishing Group UK 2017-07-14 /pmc/articles/PMC5511142/ /pubmed/28710484 http://dx.doi.org/10.1038/s41598-017-05842-8 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Min, Kyungtaek
Kim, Sookyoung
Kim, Chang Gun
Kim, Sunghwan
Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer
title Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer
title_full Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer
title_fullStr Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer
title_full_unstemmed Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer
title_short Colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer
title_sort colored and fluorescent nanofibrous silk as a physically transient chemosensor and vitamin deliverer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511142/
https://www.ncbi.nlm.nih.gov/pubmed/28710484
http://dx.doi.org/10.1038/s41598-017-05842-8
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