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IgG3-antigen complexes are deposited on follicular dendritic cells in the presence of C1q and C3

IgG3, passively administered together with small proteins, induces enhanced primary humoral responses against these proteins. We previously found that, within 2 h of immunization, marginal zone (MZ) B cells capture IgG3-antigen complexes and transport them into splenic follicles and that this requir...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Ding, Zhoujie, Heyman, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511153/
https://www.ncbi.nlm.nih.gov/pubmed/28710441
http://dx.doi.org/10.1038/s41598-017-05704-3

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