Endothelial cells by inactivation of VHL gene direct angiogenesis, not vasculogenesis via Twist1 accumulation associated with hemangioblastoma neovascularization

Inactivation of the VHL tumour suppressor gene is a highly frequent genetic event in the carcinogenesis of central nervous system-(CNS) hemangioblastomas (HBs). The patterning of the similar embryonic vasculogenesis is an increasing concern in HB-neovascularization, and the classic vascular endothel...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Chen, Dan-Qi, Chen, Ming-Yu, Ji, Kai-Yuan, Ma, De-Xuan, Zhou, Liang-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511164/
https://www.ncbi.nlm.nih.gov/pubmed/28710479
http://dx.doi.org/10.1038/s41598-017-05833-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511164/
https://www.ncbi.nlm.nih.gov/pubmed/28710479
http://dx.doi.org/10.1038/s41598-017-05833-9

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