HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases

HIV-1 co-opts several host machinery to generate a permissive environment for viral replication and transmission. In this work we reveal how HIV-1 impacts the host translation and intracellular vesicular trafficking machineries for protein synthesis and to impede the physiological late endosome/lyso...

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Detalles Bibliográficos
Autores principales: Cinti, Alessandro, Le Sage, Valerie, Milev, Miroslav P., Valiente-Echeverría, Fernando, Crossie, Christina, Miron, Marie-Joelle, Panté, Nelly, Olivier, Martin, Mouland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511174/
https://www.ncbi.nlm.nih.gov/pubmed/28710431
http://dx.doi.org/10.1038/s41598-017-05410-0

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