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Effects of Lipoic Acid on High-Fat Diet-Induced Alteration of Synaptic Plasticity and Brain Glucose Metabolism: A PET/CT and (13)C-NMR Study

High-fat diet (HFD)-induced obesity is accompanied by insulin resistance and compromised brain synaptic plasticity through the impairment of insulin-sensitive pathways regulating neuronal survival, learning, and memory. Lipoic acid is known to modulate the redox status of the cell and has insulin mi...

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Detalles Bibliográficos
Autores principales:	Liu, Zhigang, Patil, Ishan, Sancheti, Harsh, Yin, Fei, Cadenas, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511189/ https://www.ncbi.nlm.nih.gov/pubmed/28710347 http://dx.doi.org/10.1038/s41598-017-05217-z

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