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High Resolution Imaging of DNA Methylation Dynamics using a Zebrafish Reporter
As one of the major epigenetic modifications, DNA methylation is constantly regulated during embryonic development, cell lineage commitment, and pathological processes. To facilitate real-time observation of DNA methylation, we generated a transgenic zebrafish reporter of DNA methylation (zebraRDM)...
Autores principales: | Zhang, Ranran, Liu, Lian, Yao, Yuxiao, Fei, Fei, Wang, Feng, Yang, Qian, Gui, Yonghao, Wang, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511286/ https://www.ncbi.nlm.nih.gov/pubmed/28710355 http://dx.doi.org/10.1038/s41598-017-05648-8 |
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