Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

Phospholipids occurring in cell membranes and lipoproteins are converted into oxidized phospholipids (OxPL) by oxidative stress promoting atherosclerotic plaque formation. Here, OxPL were characterized as novel targets in acute and chronic inflammatory pain. Oxidized 1-palmitoyl-2-arachidonoyl-sn-gl...

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Detalles Bibliográficos
Autores principales: Oehler, Beatrice, Kistner, Katrin, Martin, Corinna, Schiller, Jürgen, Mayer, Rafaela, Mohammadi, Milad, Sauer, Reine-Solange, Filipovic, Milos R., Nieto, Francisco R., Kloka, Jan, Pflücke, Diana, Hill, Kerstin, Schaefer, Michael, Malcangio, Marzia, Reeh, Peter W., Brack, Alexander, Blum, Robert, Rittner, Heike L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511297/
https://www.ncbi.nlm.nih.gov/pubmed/28710476
http://dx.doi.org/10.1038/s41598-017-05348-3

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