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Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures

The mycobacteria RNA polymerase (RNAP) is a target for antimicrobials against tuberculosis, motivating structure/function studies. Here we report a 3.2 Å-resolution crystal structure of a Mycobacterium smegmatis (Msm) open promoter complex (RPo), along with structural analysis of the Msm RPo and a p...

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Detalles Bibliográficos
Autores principales:	Hubin, Elizabeth A., Lilic, Mirjana, Darst, Seth A., Campbell, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511352/ https://www.ncbi.nlm.nih.gov/pubmed/28703128 http://dx.doi.org/10.1038/ncomms16072

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