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Effect of Cigarette Smoking on Haematological Parameters in Healthy Population

OBJECTIVE: Tobacco cigarette smoking is one of the major leading causes of death throughout the world. Smoking has both acute and chronic effect on haematological parameters. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics...

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Autores principales: Malenica, Maja, Prnjavorac, Besim, Bego, Tamer, Dujic, Tanja, Semiz, Sabina, Skrbo, Selma, Gusic, Amar, Hadzic, Ajla, Causevic, Adlija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AVICENA, d.o.o., Sarajevo 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511531/
https://www.ncbi.nlm.nih.gov/pubmed/28790546
http://dx.doi.org/10.5455/medarh.2017.71.132-136
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author Malenica, Maja
Prnjavorac, Besim
Bego, Tamer
Dujic, Tanja
Semiz, Sabina
Skrbo, Selma
Gusic, Amar
Hadzic, Ajla
Causevic, Adlija
author_facet Malenica, Maja
Prnjavorac, Besim
Bego, Tamer
Dujic, Tanja
Semiz, Sabina
Skrbo, Selma
Gusic, Amar
Hadzic, Ajla
Causevic, Adlija
author_sort Malenica, Maja
collection PubMed
description OBJECTIVE: Tobacco cigarette smoking is one of the major leading causes of death throughout the world. Smoking has both acute and chronic effect on haematological parameters. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics in healthy smokers. SUBJECTS AND METHOD: One hundred and fifty six subjects participated in this study, 56 smokers and 100 non-smokers. The smokers were regularly consuming 10-20 cigarettes per day for at least 3 years. Complete blood cell count was analyzed by CELL-DYN 3700 fully automatic haematological analyzer. RESULTS: The smokers had significantly higher levels of white blood cell (p<0,001), hemoglobin (p=0,042), mean corpuscular volume (p=0,001) and mean corpuscular hemoglobin concentration (p<0,001). All other measured parameters did not differ significantly. Cigarette smoking caused a significant increase (p<0,001) in red blood cells, white blood cells (p=0,040), hemoglobin (p<0,001), hematocrit (p=0,047) and mean corpuscular hemoglobin (p<0,001) in males in comparison to female smokers. CONCLUSION: In conclusion, our study showed that continuous cigarette smoking has severe adverse effects on haematological parameters (e.g., hemoglobin, white blood cells count, mean corpuscular volume, mean corpuscular hemoglobin concentration, red blood cells count, hematocrit) and these alterations might be associated with a greater risk for developing atherosclerosis, polycythemia vera, chronic obstructive pulmonary disease and/or cardiovascular diseases.
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spelling pubmed-55115312017-08-08 Effect of Cigarette Smoking on Haematological Parameters in Healthy Population Malenica, Maja Prnjavorac, Besim Bego, Tamer Dujic, Tanja Semiz, Sabina Skrbo, Selma Gusic, Amar Hadzic, Ajla Causevic, Adlija Med Arch Original Paper OBJECTIVE: Tobacco cigarette smoking is one of the major leading causes of death throughout the world. Smoking has both acute and chronic effect on haematological parameters. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics in healthy smokers. SUBJECTS AND METHOD: One hundred and fifty six subjects participated in this study, 56 smokers and 100 non-smokers. The smokers were regularly consuming 10-20 cigarettes per day for at least 3 years. Complete blood cell count was analyzed by CELL-DYN 3700 fully automatic haematological analyzer. RESULTS: The smokers had significantly higher levels of white blood cell (p<0,001), hemoglobin (p=0,042), mean corpuscular volume (p=0,001) and mean corpuscular hemoglobin concentration (p<0,001). All other measured parameters did not differ significantly. Cigarette smoking caused a significant increase (p<0,001) in red blood cells, white blood cells (p=0,040), hemoglobin (p<0,001), hematocrit (p=0,047) and mean corpuscular hemoglobin (p<0,001) in males in comparison to female smokers. CONCLUSION: In conclusion, our study showed that continuous cigarette smoking has severe adverse effects on haematological parameters (e.g., hemoglobin, white blood cells count, mean corpuscular volume, mean corpuscular hemoglobin concentration, red blood cells count, hematocrit) and these alterations might be associated with a greater risk for developing atherosclerosis, polycythemia vera, chronic obstructive pulmonary disease and/or cardiovascular diseases. AVICENA, d.o.o., Sarajevo 2017-04 /pmc/articles/PMC5511531/ /pubmed/28790546 http://dx.doi.org/10.5455/medarh.2017.71.132-136 Text en Copyright: © 2017 Maja Malenica, Besim Prnjavorac, Tamer Bego, Tanja Dujic, Sabina Semiz, Selma Skrbo, Amar Gusic, Ajla Hadzic, Adlija Causevic http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Malenica, Maja
Prnjavorac, Besim
Bego, Tamer
Dujic, Tanja
Semiz, Sabina
Skrbo, Selma
Gusic, Amar
Hadzic, Ajla
Causevic, Adlija
Effect of Cigarette Smoking on Haematological Parameters in Healthy Population
title Effect of Cigarette Smoking on Haematological Parameters in Healthy Population
title_full Effect of Cigarette Smoking on Haematological Parameters in Healthy Population
title_fullStr Effect of Cigarette Smoking on Haematological Parameters in Healthy Population
title_full_unstemmed Effect of Cigarette Smoking on Haematological Parameters in Healthy Population
title_short Effect of Cigarette Smoking on Haematological Parameters in Healthy Population
title_sort effect of cigarette smoking on haematological parameters in healthy population
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511531/
https://www.ncbi.nlm.nih.gov/pubmed/28790546
http://dx.doi.org/10.5455/medarh.2017.71.132-136
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