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Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy

Importance: Polymorphic expression of drug metabolizing enzymes affects the metabolism of antidepressants, and thus can contribute to drug response and/or adverse events. Pregnancy itself can affect CYP2D6 activity with profound variations determined by CYP2D6 genotype. Objective: To investigate the...

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Detalles Bibliográficos
Autores principales:	Bérard, Anick, Gaedigk, Andrea, Sheehy, Odile, Chambers, Christina, Roth, Mark, Bozzo, Pina, Johnson, Diana, Kao, Kelly, Lavigne, Sharon, Wolfe, Lori, Quinn, Dee, Dieter, Kristen, Zhao, Jin-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511844/ https://www.ncbi.nlm.nih.gov/pubmed/28769788 http://dx.doi.org/10.3389/fphar.2017.00402

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