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Generation and analysis of spheroids from human primary skin myofibroblasts: an experimental system to study myofibroblasts deactivation

Myofibroblasts are activated fibroblasts involved in tissue repair and cancer. They are characterized by de novo expression of α-smooth muscle actin (α-SMA), immunoregulatory phenotype and paracrine interaction with normal and tumorigenic cells leading to cell proliferation. At the end of wound-heal...

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Detalles Bibliográficos
Autores principales: Granato, Giuseppina, Ruocco, Maria R, Iaccarino, Antonino, Masone, Stefania, Calì, Gaetano, Avagliano, Angelica, Russo, Valentina, Bellevicine, Claudio, Di Spigna, Gaetano, Fiume, Giuseppe, Montagnani, Stefania, Arcucci, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511858/
https://www.ncbi.nlm.nih.gov/pubmed/28725488
http://dx.doi.org/10.1038/cddiscovery.2017.38