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Generation and analysis of spheroids from human primary skin myofibroblasts: an experimental system to study myofibroblasts deactivation
Myofibroblasts are activated fibroblasts involved in tissue repair and cancer. They are characterized by de novo expression of α-smooth muscle actin (α-SMA), immunoregulatory phenotype and paracrine interaction with normal and tumorigenic cells leading to cell proliferation. At the end of wound-heal...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511858/ https://www.ncbi.nlm.nih.gov/pubmed/28725488 http://dx.doi.org/10.1038/cddiscovery.2017.38 |