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BMP-2 induces EMT and breast cancer stemness through Rb and CD44

Bone morphogenetic protein 2 (BMP-2) has been reported to facilitate epithelial-to-mesenchymal transition (EMT) and bone metastasis in breast cancer xenograft models. To investigate the role of BMP-2 in the development of breast cancer stem cells (BCSCs), and to further elucidate the mechanisms unde...

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Detalles Bibliográficos
Autores principales: Huang, Peide, Chen, Anan, He, Weiyi, Li, Zhen, Zhang, Guanglin, Liu, Zhong, Liu, Ge, Liu, Xueting, He, Shuilian, Xiao, Gang, Huang, Feicheng, Stenvang, Jan, Brünner, Nils, Hong, An, Wang, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511860/
https://www.ncbi.nlm.nih.gov/pubmed/28725489
http://dx.doi.org/10.1038/cddiscovery.2017.39