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A Case of Atopic Myelitis with Cervical Cavernous Angioma

Atopic myelitis, a type of myelitis which appears in patients with elevated serum levels of immunoglobulin E (IgE), occurs more commonly in the cervical spinal cord, but this mechanism has not yet been elucidated. Herein, we experienced a case of atopic myelitis developed during the growth of cervic...

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Autores principales: Fukuda, Miyuki, Manabe, Hiroaki, Sasaki, Nobuhiro, Kuroda, Masayuki, Hoshimaru, Minoru, Ueda, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512020/
https://www.ncbi.nlm.nih.gov/pubmed/28757876
http://dx.doi.org/10.1155/2017/9506275
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author Fukuda, Miyuki
Manabe, Hiroaki
Sasaki, Nobuhiro
Kuroda, Masayuki
Hoshimaru, Minoru
Ueda, Shigeo
author_facet Fukuda, Miyuki
Manabe, Hiroaki
Sasaki, Nobuhiro
Kuroda, Masayuki
Hoshimaru, Minoru
Ueda, Shigeo
author_sort Fukuda, Miyuki
collection PubMed
description Atopic myelitis, a type of myelitis which appears in patients with elevated serum levels of immunoglobulin E (IgE), occurs more commonly in the cervical spinal cord, but this mechanism has not yet been elucidated. Herein, we experienced a case of atopic myelitis developed during the growth of cervical cavernous angioma caused by bleeding. A 37-year-old woman suffered from hand swelling caused by a house cat licking. At the same time when cavernous angioma had grown, she experienced a numbness in her four extremities, and multifocal peritumoral hyperintense spinal cord signals were seen. The diagnosis of atopic myelitis was made because we observed significantly elevated levels of specific IgE antibody to cat dander. Symptoms disappeared immediately after steroid pulse therapy. We subsequently resected a cavernous angioma, and eosinophil invasion was found inside it. This is the first case report of atopic myelitis which developed in association with spinal cord vascular lesions. A local blood-brain barrier breakdown due to hemorrhagic lesions of the spinal cord may have contributed to the onset of atopic myelitis.
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spelling pubmed-55120202017-07-30 A Case of Atopic Myelitis with Cervical Cavernous Angioma Fukuda, Miyuki Manabe, Hiroaki Sasaki, Nobuhiro Kuroda, Masayuki Hoshimaru, Minoru Ueda, Shigeo Case Rep Med Case Report Atopic myelitis, a type of myelitis which appears in patients with elevated serum levels of immunoglobulin E (IgE), occurs more commonly in the cervical spinal cord, but this mechanism has not yet been elucidated. Herein, we experienced a case of atopic myelitis developed during the growth of cervical cavernous angioma caused by bleeding. A 37-year-old woman suffered from hand swelling caused by a house cat licking. At the same time when cavernous angioma had grown, she experienced a numbness in her four extremities, and multifocal peritumoral hyperintense spinal cord signals were seen. The diagnosis of atopic myelitis was made because we observed significantly elevated levels of specific IgE antibody to cat dander. Symptoms disappeared immediately after steroid pulse therapy. We subsequently resected a cavernous angioma, and eosinophil invasion was found inside it. This is the first case report of atopic myelitis which developed in association with spinal cord vascular lesions. A local blood-brain barrier breakdown due to hemorrhagic lesions of the spinal cord may have contributed to the onset of atopic myelitis. Hindawi 2017 2017-07-03 /pmc/articles/PMC5512020/ /pubmed/28757876 http://dx.doi.org/10.1155/2017/9506275 Text en Copyright © 2017 Miyuki Fukuda et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fukuda, Miyuki
Manabe, Hiroaki
Sasaki, Nobuhiro
Kuroda, Masayuki
Hoshimaru, Minoru
Ueda, Shigeo
A Case of Atopic Myelitis with Cervical Cavernous Angioma
title A Case of Atopic Myelitis with Cervical Cavernous Angioma
title_full A Case of Atopic Myelitis with Cervical Cavernous Angioma
title_fullStr A Case of Atopic Myelitis with Cervical Cavernous Angioma
title_full_unstemmed A Case of Atopic Myelitis with Cervical Cavernous Angioma
title_short A Case of Atopic Myelitis with Cervical Cavernous Angioma
title_sort case of atopic myelitis with cervical cavernous angioma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512020/
https://www.ncbi.nlm.nih.gov/pubmed/28757876
http://dx.doi.org/10.1155/2017/9506275
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